产品货号：
Z14519
中文名称：
FAIM抗体
英文名称：
Anti-FAIM Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FAIM Antibody |
| 指标别名 | FAIM;FAIM1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | FAIM |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FAIM antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human FAIM.The immunogen is located within the last 50 amino acids of FAIM. |
| 计算分子量 | 20kDa |
| 成分 | FAIM Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FAIM Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion.Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL,FLIP,and a recently identified protein termed FAIM.This molecule is broadly expressed in various tissues and exists in at least three isoforms.It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity.More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite outgrowth in different neuronal systems by a mechanism involving the activation of NF-百B and the Ras-ERK pathway. |
| Uniprot ID | Q9NVQ4 |
| 基因名全称 | Fas apoptotic inhibitory molecule |
| 蛋白名全称 | Fas apoptotic inhibitory molecule |
| 推荐稀释比 | FAIM antibody can be used for detection of FAIM by Western blot at 5 ～ 10μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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